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Search Results for " interleukin 18 "

Targets

3

Compounds

60

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T16570 Pralnacasan VX-740,HMR 3480 Others
Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. Pralnacasan is an effective, non-peptide, and orally active interleukin-1β converting enzyme inhibitor (Ki: 1.4 nM). Pralnacasan has the potential ...
T10447 BAA473 Others
BAA473 is a bile acid analog that is a potent activator of the pyrin inflammasome. BAA473 can induce secretion of interleukin-18 (IL-18) through activation of the inflammasome in both myeloid and intestinal epithelial c...
T62950 IRAK4-IN-18
IRAK4-IN-18 is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) (IC50: 15 nM). IRAK4-IN-18 inhibits LPS-induced IL23 production in THP and DC cells and blocks the development of arthritis in rats,...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02824 IL-18R alpha Protein, Rat, Recombinant (hFc) Rat HEK293
Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-01928 IL-18 Protein, Rhesus, Recombinant (His) Rhesus E. coli
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-g...
TMPY-03951 IL-18R alpha Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-03273 IL-18 Protein, Mouse, Recombinant Mouse E. coli
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-g...
TMPY-00846 IL-18BP Protein, Human, Recombinant (His) Human HEK293
Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin ...
TMPY-05492 IL-18BP Protein, Human, Recombinant (aa 1-192, hFc) Human HEK293
Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin ...
TMPY-00277 IL-18 Protein, Human, Recombinant Human E. coli
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-g...
TMPY-01376 IL-18R alpha Protein, Mouse, Recombinant (His) Mouse HEK293
Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-03102 IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-05782 IL-18R alpha Protein, Mouse, Recombinant (mFc) Mouse HEK293
Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-01111 IL-18BP Protein, Mouse, Recombinant (His) Mouse HEK293
Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin ...
TMPY-05491 IL-18R alpha Protein, Human, Recombinant (hFc) Human HEK293
Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-01219 IL-18R alpha Protein, Human, Recombinant (His) Human HEK293
Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-01446 IL-18R beta/IL-18RAP Protein, Human, Recombinant (His) Human HEK293
Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-03911 IL-18R alpha Protein, Rat, Recombinant (His) Rat HEK293
Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-00345 IL-18R alpha Protein, Canine, Recombinant (His) Canine HEK293
Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-00509 IL-18R alpha Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-03901 IL-18R alpha Protein, Canine, Recombinant (hFc) Canine HEK293
Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-00984 IL-18R alpha Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-06750 IL-18R beta/IL-18RAP Protein, Rabbit, Recombinant (His) Rabbit HEK293
Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-03103 IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (His) Rhesus HEK293
Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPK-00492 IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated Cynomolgus HEK293
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggestin...
TMPJ-00072 IL-18BPd Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF-γ, which then stimulates 18BP production via NF-κB. The interact...
TMPY-06761 IL-18R beta/IL-18RAP Protein, Rat, Recombinant (His) Rat HEK293
Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPJ-00344 IL-18RAP Protein, Human, Recombinant (hFc & His) Human Human Cells
IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 a...
TMPY-03381 IL-18 Protein, Human, Recombinant (GST) Human E. coli
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-g...
TMPK-00491 IL-18BP Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggestin...
TMPJ-00074 IL-18BP Protein, Human, Recombinant (hFc) Human Human Cells
Interleukin-18-binding protein, also known as Tadekinig-alfa and IL18BP, contains 1 Ig-like C2-type domain. IL18BP is constitutively expressed and secreted in mononuclear cells. IL18BP functions as an IL18 inhibitor. IL1...
TMPY-06578 IL-18R alpha Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPY-06897 IL-18R alpha Protein, Human, Recombinant (His), Biotinylated Human HEK293
Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expres...
TMPJ-00070 IL-18 Protein, Human, Recombinant (His) Human Human Cells
Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The c...
TMPY-00844 IL-17RD Protein, Human, Recombinant (His) Human HEK293
Interleukin-17 receptor D (IL-17D) also known as Interleukin-17 receptor-like protein, is a member of the interleukine-17 receptor family. IL-17RD functions as a feedback inhibitor of fibroblast growth factor-mediated Ra...
TMPK-00076 IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated Human E. coli
Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop...
TMPJ-01056 IL-18 Protein, Mouse, Recombinant (His) Mouse E. coli
Interleukin-18 (IL-18)is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63...
TMPY-00609 IL-18R beta/IL-18RAP Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-06316 IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-01200 IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc) Human HEK293
Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPK-00661 IL-22 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeab...
TMPY-06312 IL-18R beta/IL-18RAP Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPK-01194 IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse E. coli
The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeab...
TMPY-05449 IL-33 Protein, Cynomolgus, Recombinant Cynomolgus E. coli
Interleukin 33 (IL-33), also known as DVS27 or NF-HEV (Nuclear Factor from High Endothelial Venules), is a pro-inflammatory protein and a chromatin-associated cytokine of the IL-1 family with high sequence and structural...
TMPY-02789 IL-33 Protein, Canine, Recombinant Canine E. coli
Interleukin 33 (IL-33), also known as DVS27 or NF-HEV (Nuclear Factor from High Endothelial Venules), is a pro-inflammatory protein and a chromatin-associated cytokine of the IL-1 family with high sequence and structural...
TMPY-00861 IL-33 Protein, Human, Recombinant Human E. coli
Interleukin 33 (IL-33), also known as DVS27 or NF-HEV (Nuclear Factor from High Endothelial Venules), is a pro-inflammatory protein and a chromatin-associated cytokine of the IL-1 family with high sequence and structural...
TMPJ-00850 ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) Mouse Human Cells
ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes....
TMPK-00512 IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His) Cynomolgus HEK293
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced I...
TMPK-00317 IL-18R alpha Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced I...
TMPK-00316 IL-18R alpha Protein, Human, Recombinant (His & Avi) Human HEK293
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced I...
TMPK-00332 IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi) Human HEK293
The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R...
TMPK-00638 IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R...
TMPK-00082 IL-18BP Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggestin...
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IL-18R alpha Protein, Rat, Recombinant (hFc)
TMPY-02824
Species: Rat
Expression System: HEK293
IL-18 Protein, Rhesus, Recombinant (His)
TMPY-01928
Species: Rhesus
Expression System: E. coli
IL-18R alpha Protein, Cynomolgus, Recombinant (hFc)
TMPY-03951
Species: Cynomolgus
Expression System: HEK293
IL-18 Protein, Mouse, Recombinant
TMPY-03273
Species: Mouse
Expression System: E. coli
IL-18BP Protein, Human, Recombinant (His)
TMPY-00846
Species: Human
Expression System: HEK293
IL-18BP Protein, Human, Recombinant (aa 1-192, hFc)
TMPY-05492
Species: Human
Expression System: HEK293
IL-18 Protein, Human, Recombinant
TMPY-00277
Species: Human
Expression System: E. coli
IL-18R alpha Protein, Mouse, Recombinant (His)
TMPY-01376
Species: Mouse
Expression System: HEK293
IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (hFc)
TMPY-03102
Species: Rhesus
Expression System: HEK293
IL-18R alpha Protein, Mouse, Recombinant (mFc)
TMPY-05782
Species: Mouse
Expression System: HEK293
IL-18BP Protein, Mouse, Recombinant (His)
TMPY-01111
Species: Mouse
Expression System: HEK293
IL-18R alpha Protein, Human, Recombinant (hFc)
TMPY-05491
Species: Human
Expression System: HEK293
IL-18R alpha Protein, Human, Recombinant (His)
TMPY-01219
Species: Human
Expression System: HEK293
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His)
TMPY-01446
Species: Human
Expression System: HEK293
IL-18R alpha Protein, Rat, Recombinant (His)
TMPY-03911
Species: Rat
Expression System: HEK293
IL-18R alpha Protein, Canine, Recombinant (His)
TMPY-00345
Species: Canine
Expression System: HEK293
IL-18R alpha Protein, Cynomolgus, Recombinant (His)
TMPY-00509
Species: Cynomolgus
Expression System: HEK293
IL-18R alpha Protein, Canine, Recombinant (hFc)
TMPY-03901
Species: Canine
Expression System: HEK293
IL-18R alpha Protein, Mouse, Recombinant (His & hFc)
TMPY-00984
Species: Mouse
Expression System: HEK293
IL-18R beta/IL-18RAP Protein, Rabbit, Recombinant (His)
TMPY-06750
Species: Rabbit
Expression System: HEK293
IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (His)
TMPY-03103
Species: Rhesus
Expression System: HEK293
IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
TMPK-00492
Species: Cynomolgus
Expression System: HEK293
IL-18BPd Protein, Mouse, Recombinant (hFc)
TMPJ-00072
Species: Mouse
Expression System: Human Cells
IL-18R beta/IL-18RAP Protein, Rat, Recombinant (His)
TMPY-06761
Species: Rat
Expression System: HEK293
IL-18RAP Protein, Human, Recombinant (hFc & His)
TMPJ-00344
Species: Human
Expression System: Human Cells
IL-18 Protein, Human, Recombinant (GST)
TMPY-03381
Species: Human
Expression System: E. coli
IL-18BP Protein, Cynomolgus, Recombinant (His)
TMPK-00491
Species: Cynomolgus
Expression System: HEK293
IL-18BP Protein, Human, Recombinant (hFc)
TMPJ-00074
Species: Human
Expression System: Human Cells
IL-18R alpha Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06578
Species: Human
Expression System: HEK293
IL-18R alpha Protein, Human, Recombinant (His), Biotinylated
TMPY-06897
Species: Human
Expression System: HEK293
IL-18 Protein, Human, Recombinant (His)
TMPJ-00070
Species: Human
Expression System: Human Cells
IL-17RD Protein, Human, Recombinant (His)
TMPY-00844
Species: Human
Expression System: HEK293
IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated
TMPK-00076
Species: Human
Expression System: E. coli
IL-18 Protein, Mouse, Recombinant (His)
TMPJ-01056
Species: Mouse
Expression System: E. coli
IL-18R beta/IL-18RAP Protein, Mouse, Recombinant (His)
TMPY-00609
Species: Mouse
Expression System: Baculovirus-Insect Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06316
Species: Human
Expression System: HEK293
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc)
TMPY-01200
Species: Human
Expression System: HEK293
IL-22 Protein, Cynomolgus, Recombinant (His)
TMPK-00661
Species: Cynomolgus
Expression System: HEK293
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06312
Species: Human
Expression System: HEK293
IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-01194
Species: Mouse
Expression System: E. coli
IL-33 Protein, Cynomolgus, Recombinant
TMPY-05449
Species: Cynomolgus
Expression System: E. coli
IL-33 Protein, Canine, Recombinant
TMPY-02789
Species: Canine
Expression System: E. coli
IL-33 Protein, Human, Recombinant
TMPY-00861
Species: Human
Expression System: E. coli
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
TMPJ-00850
Species: Mouse
Expression System: Human Cells
IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His)
TMPK-00512
Species: Cynomolgus
Expression System: HEK293
IL-18R alpha Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00317
Species: Human
Expression System: HEK293
IL-18R alpha Protein, Human, Recombinant (His & Avi)
TMPK-00316
Species: Human
Expression System: HEK293
IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi)
TMPK-00332
Species: Human
Expression System: HEK293
IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus, Recombinant (His)
TMPK-00638
Species: Cynomolgus
Expression System: HEK293
IL-18BP Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00082
Species: Human
Expression System: HEK293
TargetMol